Scurge: Hive

Scurge: Hive is an action-adventure video game by Orbital Media released for the Game Boy Advance and Nintendo DS in 2006. The game follows the protagonist Jenosa Arma, a bounty huntress tasked with hunting a parasitic lifeform called the "Scurge" an alien entity capable of rapidly adapting to and infecting biological, mechanical, and digital systems, including the player. Throughout the game, Jenosa Arma will have to battle various forms of the Scurge virus and race against the clock as the parasite slowly takes over Jenosa's body. The gameplay takes place in an isometric perspective.